Air improvement recommendations for the San Francisco Bay area The Stanford-Ames NASA/asee SummerFaculty Systems Design workshop Final report

Air pollution monitoring and pollutant source surveillance system, and effective regulations and enforcement means for San Francisco Bay are

Oscillatory Energy Exchange Between Waves Coupled by a Dynamic Artificial Crystal

We describe a general mechanism of controllable energy exchange between waves propagating in a dynamic artificial crystal. We show that if a spatial periodicity is temporarily imposed on the transmission properties of a wave-carrying medium whilst a wave is inside, this wave is coupled to a secondary counter-propagating wave and energy oscillates between the two. The oscillation frequency is determined by the width of the spectral band gap created by the periodicity and the frequency difference between the coupled waves. The effect is demonstrated with spin waves in a dynamic magnonic crystal.Comment: 5 pages, 4 figure

Breast cancer biomarkers predict weight loss after gastric bypass surgery

<p>Abstract</p> <p>Background</p> <p>Obesity has long been associated with postmenopausal breast cancer risk and more recently with premenopausal breast cancer risk. We previously observed that nipple aspirate fluid (n) levels of prostate specific antigen (PSA) were associated with obesity. Serum (s) levels of adiponectin are lower in women with higher body mass index (BMI) and with breast cancer. We conducted a prospective study of obese women who underwent gastric bypass surgery to determine: 1) change in n- and s-adiponectin and nPSA after surgery and 2) if biomarker change is related to change in BMI. Samples (30-s, 28-n) and BMI were obtained from women 0, 3, 6 and 12 months after surgery.</p> <p>Findings</p> <p>There was a significant increase after surgery in pre- but not postmenopausal women at all time points in s-adiponectin and at 3 and 6 months in n-adiponectin. Low n-PSA and high s-adiponectin values were highly correlated with decrease in BMI from baseline.</p> <p>Conclusions</p> <p>Adiponectin increases locally in the breast and systemically in premenopausal women after gastric bypass. s-adiponectin in pre- and nPSA in postmenopausal women correlated with greater weight loss. This study provides preliminary evidence for biologic markers to predict weight loss after gastric bypass surgery.</p

Human listeners' perception of behavioural context and core affect dimensions in chimpanzee vocalizations

Vocalizations linked to emotional states are partly conserved among phylogenetically related species. This continuity may allow humans to accurately infer affective information from vocalizations produced by chimpanzees. In two pre-registered experiments, we examine human listeners' ability to infer behavioural contexts (e.g. discovering food) and core affect dimensions (arousal and valence) from 155 vocalizations produced by 66 chimpanzees in 10 different positive and negative contexts at high, medium or low arousal levels. In experiment 1, listeners (n = 310), categorized the vocalizations in a forced-choice task with 10 response options, and rated arousal and valence. In experiment 2, participants (n = 3120) matched vocalizations to production contexts using yes/no response options. The results show that listeners were accurate at matching vocalizations of most contexts in addition to inferring arousal and valence. Judgments were more accurate for negative as compared to positive vocalizations. An acoustic analysis demonstrated that, listeners made use of brightness and duration cues, and relied on noisiness in making context judgements, and pitch to infer core affect dimensions. Overall, the results suggest that human listeners can infer affective information from chimpanzee vocalizations beyond core affect, indicating phylogenetic continuity in the mapping of vocalizations to behavioural contexts

Raman cooling and heating of two trapped Ba+ ions

We study cooling of the collective vibrational motion of two 138Ba+ ions confined in an electrodynamic trap and irradiated with laser light close to the resonances S_1/2-P_1/2 (493 nm) and P_1/2-D_3/2 (650 nm). The motional state of the ions is monitored by a spatially resolving photo multiplier. Depending on detuning and intensity of the cooling lasers, macroscopically different motional states corresponding to different ion temperatures are observed. We also derive the ions' temperature from detailed analytical calculations of laser cooling taking into account the Zeeman structure of the energy levels involved. The observed motional states perfectly match the calculated temperatures. Significant heating is observed in the vicinity of the dark resonances of the Zeeman-split S_1/2-D_3/2 Raman transitions. Here two-photon processes dominate the interaction between lasers and ions. Parameter regimes of laser light are identified that imply most efficient laser cooling.Comment: 8 pages, 5 figure

Local and global Fokker-Planck neoclassical calculations showing flow and bootstrap current modification in a pedestal

In transport barriers, particularly H-mode edge pedestals, radial scale lengths can become comparable to the ion orbit width, causing neoclassical physics to become radially nonlocal. In this work, the resulting changes to neoclassical flow and current are examined both analytically and numerically. Steep density gradients are considered, with scale lengths comparable to the poloidal ion gyroradius, together with strong radial electric fields sufficient to electrostatically confine the ions. Attention is restricted to relatively weak ion temperature gradients (but permitting arbitrary electron temperature gradients), since in this limit a delta-f (small departures from a Maxwellian distribution) rather than full-f approach is justified. This assumption is in fact consistent with measured inter-ELM H-Mode edge pedestal density and ion temperature profiles in many present experiments, and is expected to be increasingly valid in future lower collisionality experiments. In the numerical analysis, the distribution function and Rosenbluth potentials are solved for simultaneously, allowing use of the exact field term in the linearized Fokker-Planck collision operator. In the pedestal, the parallel and poloidal flows are found to deviate strongly from the best available conventional neoclassical prediction, with large poloidal variation of a different form than in the local theory. These predicted effects may be observable experimentally. In the local limit, the Sauter bootstrap current formulae appear accurate at low collisionality, but they can overestimate the bootstrap current near the plateau regime. In the pedestal ordering, ion contributions to the bootstrap and Pfirsch-Schluter currents are also modified

Celecoxib concentration predicts decrease in prostaglandin E2 concentrations in nipple aspirate fluid from high risk women

<p>Abstract</p> <p>Background</p> <p>Epidemiologic studies suggest that long term low dose celecoxib use significantly lowers breast cancer risk. We previously demonstrated that 400 mg celecoxib taken twice daily for 2 weeks lowered circulating plasma and breast nipple aspirate fluid (NAF) prostaglandin (PG)E₂concentrations in post- but not premenopausal high risk women. We hypothesized that circulating concentrations of celecoxib influenced PGE₂response, and that plasma levels of the drug are influenced by menopausal status. To address these hypotheses, the aims of the study were to determine: 1) if circulating plasma concentrations of celecoxib correlated with the change in plasma or NAF PGE₂concentrations from baseline to end of treatment, and 2) whether menopausal status influenced circulating levels of celecoxib.</p> <p>Methods</p> <p>Matched NAF and plasma were collected from 46 high risk women who were administered celecoxib twice daily for two weeks, 20 subjects receiving 200 mg and 26 subjects 400 mg of the agent. NAF and plasma samples were collected before and 2 weeks after taking celecoxib.</p> <p>Results</p> <p>In women taking 400 mg bid celecoxib, plasma concentrations of the agent correlated inversely with the change in NAF PGE₂levels from pre- to posttreatment. Nonsignificant trends toward higher celecoxib levels were observed in post- compared to premenopausal women. There was a significant decrease in NAF but not plasma PGE₂concentrations in postmenopausal women who took 400 mg celecoxib (p = 0.03).</p> <p>Conclusion</p> <p>In high risk women taking 400 mg celecoxib twice daily, plasma concentrations of celecoxib correlated with downregulation of PGE₂production by breast tissue. Strategies synergistic with celecoxib to downregulate PGE₂are of interest, in order to minimize the celecoxib dose required to have an effect.</p